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NeuroViz Neural atlas explorer

Illustrative research workflow

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Prepare a hypothalamic reference cohort

What does the DMH Pvalb-positive cohort contribute to planning a later comparison?

Scientific context

DMH, 12 HY GABA, and measured Pvalb produce 189 matching cells in one public specimen in this release.

The spatial coverage view and export dialog preserve the filters used to construct the reference cohort.

A careful workflow

  1. Set Display limit to 100,000 through the Explorer UI.
  2. Apply the recorded source filters and review displayed versus matching counts.
  3. Inspect provenance before export or downstream interpretation.

Live Explorer walkthrough

What the current app shows

These are browser captures of the public Allen MERFISH release in NeuroViz. Open this captured cohort in Explorer.

  1. Explorer showing a DMH hypothalamic reference cohort.
    Figure 1Apply DMH, 12 HY GABA, and measured Pvalb at 100,000.

    189 matching cells define the reference cohort.

    Explore this step

    A DMH reference cohort documents what one specimen can contribute. Click to enlarge.
  2. Rotated view of the DMH reference cohort.
    Figure 2Review the coverage image.

    The cohort remains visible in anatomical context.

    Explore this step

    Rotated spatial coverage, not disease/control results. Click to enlarge.
  3. Explorer export dialog for DMH reference cohort.
    Figure 3Open the live export dialog.

    The selection can be handed to a later analysis.

    Explore this step

    The live export dialog carries this cohort to future study design. Click to enlarge.

Scope

These captures describe the public release and support cohort definition and record review; quantitative validation remains a downstream analysis step.

Useful deliverable

A reusable DMH cohort definition and export-ready selection.

Current capability and extensions

Explorer provides one public specimen's cells, source context, and export controls; it does not supply comparison groups or replicates.

Meaningful pilot success criteria

A later study can add its own groups, replicates, and analysis plan.