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NeuroViz Neural atlas explorer

Illustrative research workflow

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Choose midbrain cells for follow-up

Which SNc cells and source sections merit a closer look before follow-up work?

Scientific context

SNc, 21 MB Dopa, 215 SNc-VTA-RAmb Foxa1 Dopa, and measured Th yield 231 matching cells; the selected follow-up record comes from section C57BL6J-638850.29.

The cell-only cohort view shows the local distribution. The inspector separately shows the selected cell's taxonomy, source section, and measured Th value.

A careful workflow

  1. Set Display limit to 100,000 through the Explorer UI.
  2. Apply the recorded source filters and review displayed versus matching counts.
  3. Inspect provenance before export or downstream interpretation.

Live Explorer walkthrough

What the current app shows

These are browser captures of the public Allen MERFISH release in NeuroViz. Open this captured cohort in Explorer.

  1. Cell-only close view of the SNc Foxa1 Dopa Th cohort.
    Figure 1Apply SNc, MB Dopa, Foxa1 Dopa, and measured Th at 100,000.

    231 matching cells define the starting cohort.

    Explore this step

    A focused cell-only view shows the local SNc / Foxa1 Dopa / Th cohort without the brain mesh obscuring it. Click to enlarge.
  2. Focused SNc Foxa1 Dopa cell with inspector.
    Figure 2Open the selected-cell inspector.

    The inspector shows the selected cell's taxonomy, source section, and measured Th value; it is not a spatial view.

    Explore this step

    Focused selected-cell review supports candidate section discussion. Click to enlarge.
  3. Selection inspector for SNc Foxa1 Dopa source section.
    Figure 3Review the source-section view.

    Section C57BL6J-638850.29 is available for follow-up.

    Explore this step

    A source-section-constrained record is reviewable before commitment. Click to enlarge.

Scope

These captures describe the public release and support cohort definition and record review; quantitative validation remains a downstream analysis step.

Useful deliverable

A short list of source-traceable midbrain candidates.

Current capability and extensions

Explorer supports candidate selection and record inspection.

Meaningful pilot success criteria

The team can choose cells and sections to evaluate with its own experimental criteria.